A m6-month-old breast-fed infant was well until 16 weeks of age, when he became increasingly irritable and a rash developed around his mouth. The rash was progressively enlarging but did not appear to be pruritic or painful as far as the mother could tell. He was taken to see his pediatrician approximately 2 weeks following the onset of the rash for evaluation. At that time no other abnormalities on physical examination were noted nor did there appear to be any signs of systemic infection. He had no history of fever or obvious symptoms of an upper respiratory or gastrointestinal infection according to his mother. The patient had no travel history. He had been previously healthy with no hospitalizations. He was receiving no medications and his immunizations were reported to be up to date. There were no day care contacts. There was no family history of similar skin conditions. His growth and development were appropriate for age. An irritant effect from drooling was suspected and a referral to a dermatologist was made to rule out other possible etiologies. By the time of his dermatology appointment the rash had spread from his mouth to the diaper area and then to his hands and feet. The diagnosis of a yeast infection was made and the infant was treated with aquaphor, topical steroids, and antifungal agents without improvement.On physical examination, the infant was irritable but interactive and appeared to be well-nourished and otherwise healthy. His temperature was 97.7°F orally; pulse, 110 beats per minute; and respiratory rate, 24 breaths per minute. Oral examination revealed moist mucous membranes without erythema, exudate, or tonsillar enlargement. No lymphadenopathy was present. His lungs were clear and there was no Clin
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.