IntroductionHealth services generate large amounts of routine health data (eg, administrative databases, disease registries and electronic health records), which have important secondary uses for research. Increases in the availability and the ability to access and analyse large amounts of data represent a major opportunity for conducting studies on the possible relationships between complex diseases. The objective of this study will be to evaluate the design, methods and reporting of studies conducted using observational routinely collected health data for investigating the link between cancer and neurodegenerative diseases.Methods and analysisThis is the protocol for a meta-research study. We registered the study protocol within the Open Science Framework: https://osf.io/h2qjg. We will evaluate observational studies (eg, cohort and case–control) conducted using routinely collected health data for investigating the associations between cancer and neurodegenerative diseases (such as Alzheimer’s disease, amyotrophic lateral sclerosis/motor neuron disease, Huntington’s disease, multiple sclerosis and Parkinson’s disease). The following electronic databases will be searched (from their inception onwards): MEDLINE, Embase and Web of Science Core Collection. Screening and selection of articles will be conducted by at least two researchers. Potential discrepancies will be resolved via discussion. Design, methods and reporting characteristics in each article will be extracted using a standardised data extraction form. Information on general, methodological and transparency items will be reported. We will summarise our findings with tables and graphs (eg, bar charts, forest plots).Ethics and disseminationDue to the nature of the proposed study, no ethical approval will be required. We plan to publish the full study in an open access peer-reviewed journal and disseminate the findings at scientific conferences and via social media. All data will be deposited in a cross-disciplinary public repository.
El proyecto SciELO se constituye como una iniciativa pionera del movimiento de acceso abierto para la publicación de revistas científicas editadas en países en desarrollo y de habla no inglesa.El artículo comienza revisando los orígenes del proyecto SciELO en Brasil en 1998 y su desarrollo como red cooperativa extendida a 14 países iberoamericanos y Sudáfrica. A continuación, se centra en la iniciativa española, SciELO España, que comienza a funcionar en 2001 con 4 revistas y que en la actualidad incluye 60 revistas y más de 40.000 artículos. Asimismo, se destacan los hitos conseguidos a nivel científico y de respaldo de la comunidad de editores científicos, como lo demuestran las cifras de visitas y descarga de contenidos que recibe, así como la incorporación de sus revistas en índices internacionales de prestigio como Web of Science y Scopus.
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