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Fluticasone and esomeprazole provide a similar histological response for esophageal eosinophilia. With regard to clinical response, esomeprazole was superior to fluticasone, particularly in patients with established GERD.

SUMMARY BackgroundAeroallergens have been implicated in the pathogenesis of eosinophilic oesophagitis.

SUMMARY BackgroundSome patients with a phenotypic appearance of eosinophilic oesophagitis (EoE) respond histologically to PPI, and are described as having PPI-responsive oesophageal eosinophilia (PPI-REE). It is unclear if PPI-REE is a GERDrelated phenomenon, a subtype of EoE, or a completely unique entity.