Two flavonols, quercetin (1) and quercitrin (2), were isolated from the leaves of Zanthoxylum piperitum. Their structures were established by UV, one- and two-dimensional NMR, and mass spectroscopic methods. Quercetin showed significant inhibition against mushroom tyrosinase with an IC50 value of 3.8 microg/ml, and appeared to inhibit the polyphenol oxidase activity of tyrosinase in a competitive manner (Ki = 10 +/- 0.20 microM) when L-tyrosine was used as a substrate, although it did not inhibit the melanin production of Streptomyces bikiniensis.
Corner mouth lift is in increasing demand among young patients in East Asia. Although various surgical methods exist for corner mouth lift, many patients are reluctant to undergo surgery due to fears of postsurgical scarring. We present a new technique aimed at reducing postoperative scarring. The technique involves triangular excision of the corner of the mouth and incision of the commissure with transposition of a lateral vermilion flap to lift the corner of the mouth. The muscle around the corner of the mouth is dissected to release tension. The corner mouth lift was successfully performed in all patients. It can be effectively used even in patients, such as young Asian women, who are susceptible to hypertrophic scars.
The purpose of this study is to make the target condition of experimental assessment based on the standard EN1264. To achieve this purpose, the characteristic errors, which are caused by characteristics of experimental setup and prevent the results from meeting the target condition, should be removed. This study proposes an experimental setup and suggests a control strategy based on standard EN1264. For the specifications of the experimental setup, the essential equipment and the configuration of the heat production system were deduced. For a proper control strategy, possible control strategies were derived by investigating the control-related factors such as reference points and control algorithms, and the most proper control strategy was validated by experimental assessment. Practical application: This study presents an experimental assessment to evaluate the thermal output of radiant floor heating systems based on the standard EN1264 referenced by ISO11855-2:2012. The proposed experimental assessment method will be able to supplement ISO11855-2:2012 and contribute to the development of thermally effective radiant heating panels. Therefore, it is expected that the results will be helpful to researchers for indoor environment, heating, ventilating, and air conditioning engineers, system manufacturers, and those who want to analyze the thermal output of radiant floor heating panels based on ISO 11855-2:2012.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.