Modern agriculture, practiced after the “green revolution” worldwide, aims to maximize production in order to provide food for the growing world population. Thus, farmers are required to modernize their practices through the mechanization of land use and, above all, the use of chemical pesticides to control agricultural pests. However, in addition to combating the target pest, chemical pesticides indirectly affect a wide range of species, including humans, leading to health damage. Among the main problems caused by the use of pesticides is the genotoxicity caused by chronic exposure. The present study aims to verify the occurrence of genetic damage in farmers who are occupationally exposed to agrochemicals compared to people of other professions that do not use toxic substances (control group). The research was conducted with 36 male participants (18 farmers and 18 control group, ages 24–71 for the farmer group and 22–61 for the control group). The comet assay and micronucleus test results revealed a higher rate of genetic damage in the group of farmers than in the control group. A questionnaire answered by the farmers showed that the Personal Protect Equipment (PPE) is used incorrectly or not used. In summary, our results indicate that farmers are exposed to occupational hazards. To mitigate this risk, we conducted awareness campaigns to notify the farmers of the risks and highlight the importance of using PPE correctly. Intensive efforts and training are thus required to build an awareness of safety practices and change the attitudes of farm workers in the hope of preventing harmful environmental and anthropogenic effects.

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