Many students of the coronary circulation must have noted that the ventricular zone affected by ligating a large coronary branch not only appears cyanotic and dilated, but that it seems to alter in its mode of contraction. The detailed and sequential changes in contraction are not easily followed by the unaided eye and so far have not been recorded myographically. The reasons for this were the lack of an adequate and suitable myograph and a technic for the application of one to a limited ventricular surface so that records obtained represent, at least reasonably well, changes in muscle length and not predominantly artefacts due to position changes, thrusts and vibrations of the vigorously beating ventricle. This communication concerns itself with descriptions of a technique and of a type of optical myograph suitable for such studies and an analysis of the changes in optical myograms which follow clamping of a large coronary vessel. 1 The expenses of this investigation were defrayed partly from a grant to one of us (C. J. W.
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