A major problem in the control of non-specific genital infection (NSGI) (Reeve, Gerloff, Casper, Philip, Oriel, and Powis, 1974). Although direct proof cannot be obtained in the absence of experiments using human Received for publication August 7, 1973 volunteers, most observers believe that Chlamydia are pathogenic in the male urethra. Women who are sexual contacts of men with NSU often harbour the organisms in the cervix. Primary (source) contacts of these men almost invariably have a demonstrable chlamydial infection; secondary contacts are less often infected (Oriel and others, 1972). Alexander (1973) has observed that many women with chlamydial infection show clinical evidence of cervical inflammation, although Dunlop, Jones, and AlHussaini (1964) believe that a characteristic sign is the presence of follicles and other fine changes in cervical structure visible only with the operating microscope. Like men, women with genital chlamydial infection often show an immunological response (Reeve and others, 1974). If Chlamydia is accepted as a cause of NSU, its identification in a woman might be taken to indicate that she has NSGI requiring treatment.
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