Introduction:Obstructive sleep apnea (OSA), a pathology increasingly prevalent, is a complex treatable syndrome that impact morbidity and mortality with serious cardiovascular and metabolic consequences. The interest for this pathology has increased in last decades although the syndrome remains underdiagnosed. Therefore, we aimed to identify the main predictive factors and to assess the interrelationship between them and OSA severity.Methods: To this end, we performed a prospective study in a Romanian population. The study occurred for 48 months, between October 2015-september 2019, in the Sleep Disorders Center from County Emergency Clinical Hospital of Constanta. Polygraphy, blood tests, anthropometric parameters, demographic aspects were recorded for each subject. Predictive factors were disclosed using multivariate regression analysis.Results:198 patients who referred to the Sleep Disorders Center and had been evaluated for OSA were enrolled. The study population included 147 male and 51 female; age range 27-82 years old. Among the 198 individuals, 43.5% (86 patients) had moderate OSA and 56.5% (112 patients) had severe OSA. Neck circumference, waist-hip ratio, BMI, gender, age was found to be significant predictors for OSA. In addition, >50% of patients had metabolic alterations or had cardiovascular disorders. Conclusion:No single factor was usefully predictive. Patients with OSA were more likely to be male, older, obese, have a thick neck, have a significant greater prevalence of habitual snoring and excessive daytime sleepiness, have hypertension or metabolic changes.
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