Purposes. This study aimed to evaluate long-term outcomes after the application of a corrosive chemical agent for ablation of epithelial tissue as a non-surgical treatment of anal fistulas. Methods. Adult patients with symptomatic perianal fistula were prospectively included in the study. The fistula tract was irrigated with a 5% silver nitrate solution. The primary outcome measured in this study was the rate of clinical healing after long-term follow-up. Factors that may affect healing were also analysed. Results. A total of 186 patients with anal fistula were analysed. After irrigation with silver nitrate, 82 (44%) patients had complete clinical healing during a median follow-up time of 50 (7–64) months. Patients with intermittent discharge had a significantly higher rate of complete clinical healing than those with continuous discharge ( P < .04). Fistulas without abscesses or secondary tracts had a significantly higher rate of complete clinical healing than the other types ( P = .007). Conclusion. Chemical ablation of the epithelium of the anal fistula yields promising long-term outcomes in the management of anal fistulas without surgical intervention.
Study Contextual: 15-20 % Of laparoscopic sleeve gastrectomy patients need revisional surgery after LSG, because of inadequate weight loss. Aim: The aim of our study is, primarily to analyze the relationship between liquid-phase gastric emptying rate and weight loss, to find a parameter that may be the harbinger of successful weight loss after LSG. Methods: Patient records who have undergone laparoscopic sleeve gastrectomy were examined retrospectively. 44 Patients were included in the study. Preoperative weight and BMI, postoperative weight loss at first, third, and sixth months, surgical operation reports, preoperative and postoperative liquid-phase gastric emptying study values were mainly collected. Results: The male/ female ratio was 18/82. Mean age 38 (19-60), mean body mass index 48,1(40-66) kg/m² and mean (EWL%) 63,17±13,94 were found. Mean pre and post-operative gastric emptying half times were found to be (T½) 41,86 minute(min), T½ 6,82 min (p<0.0001). Significant correlation was found between patients’ post-operative third and sixth month EWL% and post-operative T½ (p=0,020, p=0,032). Patients who have post-op gastric T½ above 10 min had decreased sixth-month EWL% significantly (p=0.03). Conclusion: Post-operative gastric emptying time (T½) may be a harbinger of weight loss after LSG.
Geopolymers are obtained by use of alteration of chemical composition and crystal structures of different minerals. Use of geopolymer is an effective and environmental friendly solution in stabilization of clayey soil. The vinyl based copolymer is used as an agent as dust controller, highway soil stabilizer, asphalt admixture, concrete production, etc. In this study, strength of a clay is improved by use of a commercial geopolymer. In this regard, soil was amended with polymer ranging among 0 % to 4 %, by volume of dry soil. Unconfined compression and oedometer tests were carried out to evaluate the effects of temperature, initial water content, compaction energy on strength and compression properties of a clay soil - within an experimental framework. The results revealed that, temperature has a considerable effect on geopolymerization. Besides, under constant moisture content during curing, increasing geopolymer content and curing period causes a slight increase in strength of specimens.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.