The multiple sleep latency test may be a more sensitive measure of a drug's effect than other tests of psychomotor function. For up to 8 h after an injection of midazolam and fentanyl, patients must consider driving or operating heavy machinery unsafe activities.

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Background: Nitrous oxide (N 2 O) provides sedation for procedures that result in constant lowintensity pain. How long do individuals remain sleepy after receiving N 2 O? We hypothesized that drug effects would be apparent for an hour or more.

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