Abbreviations:12 -PGJ2, 12 -prostaglandin J2; AIF, apoptosisinducing factor; Sox-4, SRY-HMG box protein-4; z-VAD-fmk, Benzyloxycarbonyl-Val-Ala-Asp(OMe) fluoromethyl ketone
A bstract12 -P rostagland in (P G ) J2 is kn o w n to elicit an anti-n eo plastic effects via ap optosis in duction. P revious study show ed 12 -P G J 2 -induced apopto sis u tilized casp ase cascad e th ro u g h cyto chrom e c-depend en t pathw ays in H eLa cells. In this study, the cellular m echanism of 12
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