A palladium-catalyzed
three-component reaction of aryl iodides,
norbornenes, and hexamethyldisilane/hexamethyldigermane has been developed
for the assembly of highly functionalized disilanes/digermanes. The
potential synthetic utility of this methodology was highlighted by
the late-stage manipulations of natural products and the iterative
C–H bis-silylation for the synthesis of highly decorated arenes.
A novel approach to trisubstituted oxazoles has been developed that is based upon an iodine-mediated aerobic oxidative cyclization of enaminone derivatives. This transition-metal-free procedure was highly efficient and involved the removal of four hydrogen atoms under mild conditions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.