Objectives:The aim of this study was to assess relationship between CGG repeat lengths and ovarian reserve and response to controlled ovarian stimulation (COH).
Material and methods:This prospective cohort study was carried out on patients (n = 49) who were admitted to the in vitro fertilization (IVF) clinic of the Zeynep Kamil Women's and Children'
Aim: The aim of this study was to determine whether early second trimester amniotic fluid prolactin level were associated with pregnancy outcome.
Material and Method: This study included 125 women who underwent amniocentesis for variable indications. Healthy subjects with no history of drug use were included in this study. The gestational age was determined by ultrasonic examination before 10 weeks in all cases. Amniotic fluid specimens were taken while performing amniocentesis for other indications. Amniotic fluid was collected by transabdominal amniocentesis. Amniotic fluid prolactin concentrations were utilized to predict pregnancy complication among women who underwent amniocentesis due to the variable indications.
Results: Among all study population, pregnancy was unremarkable in 102 (81.6%) cases, on the other hand, most common fetal abnormality was found to be the fetal hydrops fetalis and the second most commonly encountered fetal anomaly was trisomy, intrauterine growth restriction and intrauterine fetal demise. All study population was divided into two groups as complicated (n=23) and uncomplicated (n=102) pregnancies. Amniotic fluid prolactin concentration did not have any predictive value for complicated pregnancies (AUC=0.479).
Conclusion: Our data showed; there is no relationship between early second trimester amniotic fluid prolactin level and pregnancy outcome.
OBJECTIVE: We aimed to determine the frequency of psychological distress and related factors in infertile women who underwent assisted reproductive technologies during the COVID-19 pandemic and to develop health policies accordingly.
STUDY DESIGN: This cross-sectional study was carried out with 352 infertile women who applied to the in vitro fertilization clinic between December 2020-February 2021. In the face-to-face survey study, five questionnaires were given to all participants: (1) a Questionnaire regarding the socio-demographic/general health characteristics of the patient, (2) Impact of Event Scale-Revised, (3) Beck's Depression Inventory, (4) State-Trait Anxiety Inventory -1, (5) State-Trait Anxiety Inventory-2.
RESULTS: Post-traumatic stress disorder was detected in 129 (36.6%) infertile women. In cases of diminished ovarian reserve and oocyte freezing; a significantly higher incidence of post-traumatic stress disorder was found compared to patients with unexplained infertility, polycystic ovary syndrome, and male factor infertility (p=0.004). Minimal-mild depression level was detected in 295 (83.8%) participants, and moderate-severe depression level was found in 57 (16.2%) participants. The mean State-Trait Anxiety Inventory-1 and State-Trait Anxiety Inventory-2 scores of infertile women were 43.5±6.7 and 46.6±6.3, respectively. A statistically significant relationship was found between the duration of infertility and moderate-severe anxiety according to State-Trait Anxiety Inventory-1 (p=0.046).
CONCLUSION: Our findings show that women with long-term infertility and undergoing oocyte freezing are the most affected patients by the pandemic. It would be appropriate for in vitro fertilization centers to provide psychological support to patients that have a mentally high risk of distress.
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