Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostrum and characterized as follows: Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-4)Glc, Neu5Gc(a2-8)Neu5Gc(a2-3)Gal(b1-4)Glc, Neu5Ac(a2-3)Gal(b1-4)Glc, Neu5Ac(a2-6)Gal(b1-4)GlcNAc, Neu5Gc (a2-3)Gal(b1-4)Glc, Neu5Gc(a2-6)Gal(b1-4)Glc, Neu5Gc(a2-6)Gal(b1-4)GlcNAc. In addition, an oligosaccharide nucleotide Neu5Gc(a2-6)Gal(b1-4)GlcNAca1-UDP was characterized. Molecular species of a variety of sialyl oligosaccharides found in milk and colostrum of these Bovidae were compared.Key words: addax colostrum, Bovidae milk oligosaccharides, milk sugar nucleotide, sialyl milk oligosaccharides.
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