Feeding nutrient-enriched formula without extra energy after term does not change quantity of growth but does influence type of weight gain and body composition of preterm infants. Infants fed the nutrient-enriched formula had lower FM corrected for body size at 6 months corrected age than infants fed standard formula or human milk.

An MRI study was performed in 34 preterm infants who were clinically and neurologically normal and whose cranial ultrasound revealed no or only mild abnormalities. The postconceptional age at MRI varied between 30.6 and 37 weeks. The purpose of the study was to evaluate the significance of periventricular changes in signal intensity on MRI, comparing MRI with ultrasound. T1-weighted and T2-weighted images were assessed for changes in signal intensity of the periventricular white matter relative to the remainder of the cerebral hemispheric white matter. Cerebral MRIs of 13 postterm infants were additionally investigated. In all preterm infants small localized areas of high signal intensity on T1-weighted images and low signal intensity on T2-weighted images were seen adjacent to the frontal horns of the lateral ventricles. They faded with increasing age and were no longer seen one month after term in the group of postterm infants. The areas were considered normal before term age and probably represent remnants of the germinal matrix. Periventricular echodensities corresponded with a zone of changed signal intensity within the periventricular white matter on MRI. MRI signal change correlated with the presence and location of echodensities; the MRI signal changes slowly faded away after the echodensities disappeared.

Perinatal mortality or abnormal child development occurs in one third of pregnancies with early-onset and severe hypertensive complications and is highest in the lowest GA and BW ranges.

The neonatal VZV-IgG titer is predominantly predicted by the maternal VZV-IgG titer, whereas birth weight and gestational age are much less predictive than previously reported.

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