Inappropriate PPI prescribing is common in frail older hospitalized patients, and might increase the risk of drug-drug interactions. Polypharmacy and comorbidity were independently associated with inappropriate PPI prescribing in this group.
During the first wave of the COVID-19 pandemic in spring, 2020, 22% of infants in the WHO European Region had their vaccination courses interrupted. 3 A drop in vaccination rates of almost 20% during the first UK lockdown was reported in England. 4 However, in Lothian, attendance at childhood immunisation clinics remained stable in the weeks during lockdown (appendix).When the Scottish Vaccination Transformation Programme was designed in 2018, a strong emphasis was placed on the needs of children and adults who require vaccinations. 5 This programme provided the foundation for local adaptations to immunisation efforts by the childhood immunisation team in Lothian during the first wave of the COVID-19 pandemic. Several adaptations had an important role in keeping attendance rates stable.First, vaccinations were delivered via fixed-point clinics at various locations that were accessible by public transport. Children who could not attend clinics owing to shielding could be vaccinated by mobile teams. All vaccinations were delivered with appropriate personal protective equipment in place, in line with guidance at the time.Second, changes were made to how data were collected. All vaccination data are held centrally in the Scottish Immunisation Recall System. Public Health Scotland collects and publishes vaccination uptake data for Scotland. 2 Data published in previous years began with vaccinations completed when children reached 12 months of age. By contrast, during the pandemic, much shorter periods of time were required to monitor immunisation clinic attendance (appendix) and uptake of vaccinations.Third, efforts were made to establish trust and ensure that children and their families felt looked after. All families received a personal reminder via telephone from a trained operator on Methodology.
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