In the present study of 331 patients suffering from signs/symptoms of nasal allergy, 9 nasal polyps, allergic conjunctivitis and allergic asthma, who were referred by clinician, were taken up for diagnosis of allergy with skin prick test (Ten et al. Mayo Clin Proc 70(8):783-784, 1995) and subjective improvement of patients by immunotherapy. Out of 331 patients tested 321 patients showed significant positive results and rest of them tested negative for allergy. High incidences of positive results were noted in third and fourth decade age of patients. Dust and pollen allergens were positive in most of the patients compare to insect's antigens. Among the pollen antigens tested, those of Parthenium hysterophorus was found to be the most common (30%) followed by Prosopis julifora (25%). 75.22% patients were positive to house dust, 19.33% patients were positive to Aspergillus moulds. D. farinae was the most common offender amongst the mites. Patients who attended, allergy clinic in Kamineni Hospitals during the last 4 years were referral patients, who had been on prolonged treatment without much relief. Immunotherapy was advised to patients who were having perineal allergy, in whom, medical treatment had become only palliative. Immunotherapy injections were administered subcutaneously, and their results were monitored.
Morphine and its congeners still enjoy great popularity for the relief of post-operative pain. Although their use is justified because of their additional sedative property, serious objections have also been raised against their use' because of undesirable side-effects such as respiratory depression, vomiting, hypotension and addiction.Some effective analgesics belonging to the antipyretic analgesic group have long been available and used in other branches of clinical practice with gratifying results. These drugs are free from the many undesirable side-effects of opiates. This paper presents the results of a clinical trial of dipyrone,2 a pyrazolone derivative which is being widely used as an antipyretic analgesic. MethodsThe design of the present trial was based on the suggestions of M a s o n 3 The study was carried out in 158 patients belonging to both sexes and varying in age from 18 to 54 years. They were randomly allocated to one of three groups. The first group was deliberately restricted to only thirty-one patients, who were given a placebo of 5 ml normal saline intravenously. The second group of sixty-four patients received 5 ml dipyrone solution containing 2.5 g dipyrone, intravenously. The third group of sixtythree was given 50 mg of pethidine (meperidine) hydrochloride intravenously, diluted in 5 ml normal saline. All patients had undergone an abdominal or other major operation under general anaesthesia. None of these patients had received any systemic analgesic in the premedication, during the operation or in the post-operative period. All patients had a uniform anaesthetic technique based on N,0/02 relaxant technique. The medication (placebo, dipyrone or pethidine) was given in the ward when patients were fully conscious and complained of severe pain at the site of operation. Patients with pulse rates above 120 b.p.m. and systolic blood pressure below 100 Torr were excluded from the trial.
Stress is an imbalance between environmental demands and adolescence's coping resources that disrupts the equilibrium of the adolescence. In view the objective of the present study was quantitative, pre-experimental evaluative research approach (pre-experimental one group pre-test and post-test). In the present study the target population consists of adolescent children age 14-17 years. The sample size was 100. The investigator adopted the purposive sampling technique. Assessment of pre-test perceived level of stress among adolescent was 0 (0%) adolescent had no stress, 6(6%) adolescents had mild stress, 73(73%) had moderate stress and 21 (21%) had severe stress. Assessment of post-test perceived level of stress among adolescent was 6(6%) adolescents had no stress, 79(79%) adolescents had mild stress, 11(11%) had moderate stress and 4 (4%) had severe stress. The mean score of pre-test perceived level of stress among adolescent was 43.92. The mean score of post-test perceived level of stress among adolescent was 28.04.The mean difference of perceived level of stress in pre-test and post-test was 15.88 with standard deviation in pre-test was 13.76 and post-test was 12.19 and calculated t-value was 1.92 Hence above finding concluded that relaxation therapy is effective in reducing perceived level of stress among adolescents.
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