Autism spectrum is a brain development condition that impairs an individual’s capacity to communicate socially and manifests through strict routines and obsessive–compulsive behavior. Applied behavior analysis (ABA) is the gold-standard treatment for autism spectrum disorder (ASD). However, as the number of ASD cases increases, there is a substantial shortage of licensed ABA practitioners, limiting the timely formulation, revision, and implementation of treatment plans and goals. Additionally, the subjectivity of the clinician and a lack of data-driven decision-making affect treatment quality. We address these obstacles by applying two machine learning algorithms to recommend and personalize ABA treatment goals for 29 study participants with ASD. The patient similarity and collaborative filtering methods predicted ABA treatment with an average accuracy of 81–84%, with a normalized discounted cumulative gain of 79–81% (NDCG) compared to clinician-prepared ABA treatment recommendations. Additionally, we assess the two models’ treatment efficacy (TE) by measuring the percentage of recommended treatment goals mastered by the study participants. The proposed treatment recommendation and personalization strategy are generalizable to other intervention methods in addition to ABA and for other brain disorders. This study was registered as a clinical trial on November 5, 2020 with trial registration number CTRI/2020/11/028933.

Human action recognition (HAR) in untrimmed videos can make insightful predictions of human behaviour. Previous work on HAR‐included models trained on spatial and temporal annotations and could classify limited actions from trimmed videos. These methods reported limitations such as (1) performance degradation due to the lack of precision temporal regions proposal and (2) poor adaptability of the models in the clinical domain because of unrelated actions of interest. We propose an innovative method that could analyse untrimmed behavioural videos to recommend actions of interest leading to diagnostic and functional assessments for children with Autism Spectrum Disorder (ASD). Our method entails end‐to‐end behaviour action recognition (BAR) pipeline, including child detection, temporal action localization, and actions of interest identification and classification. The model trained on the data of 400 ASD children and 125 with other developmental delays (ODD) accurately identified ASD, ODD, and Neurotypical children with 79.7%, 77.2%, and 80.8% accuracy, respectively. The model's performance on an independent benchmark Self‐Stimulatory Behaviour Dataset (SSBD) reported top‐1 accuracy of 78.57% for combined localization with action recognition, significantly higher than the earlier reported outcomes.