Poisoning is a major problem in the pediatric population. However the offending agent and the associated morbidity and mortality vary from place to place and change over a period of time and in India limited data are available on its present trend. Objectives:-To study the etio-clinical profile and outcome of childhood poisoning and intoxication. Materials and methods:-This prospective study was carried out in patients who were admitted in pediatric wards and pediatric intensive care unit of S.C.B MCH & SVPPGIP, Cuttack with history of ingestion of poison or intoxication or envenomation from March to November 2013. Results:-A total of 288 poisoning cases of <15 years of age were studied. Majority (43%) were under 5 years. Male accounting 70%. Median duration between poisoning and presentation to our hospital being 17hours.65.7% received pre-referral treatment in the form of gastric lavage, atropine etc. Snake bite (27.7%), kerosene (17.3%) and insecticide (12.4%) poisoning being the most common offending agents. Accidental exposure being 85.8%. Suicidal cases being more common in ≥11years age children (68%)(F:M 1.7:1).Most common presentation being respiratory distress(32.5%),cellulitis of limb(24.5%) & altered sensorium(18.3%). During treatment, 46.4% received antidote & 46.37% received antibiotics. Mortality being 7%.Overall, the outcome is good with 92% survival in our hospital. Conclusion: Even though most common age group affected is still ≤ 5 years, there has been a hike in suicidal rates in children. This highlights importance of spreading awareness in our community about the emerging epidemic of poisoning.

Background: Urinary tract infection (UTI) is a common bacterial infection in children. Even a single confirmed UTI is serious, due to the potential for recurrent UTI, parenchymal damage, hypertension and renal failure.

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Background. Steroid-resistant nephrotic syndrome (SRNS) is a common problem in paediatric nephrology practice. ere is currently little information on the spectrum of histopathological lesions in children presenting with SRNS in India and other south-east Asian countries. Objective. To determine the histopathological lesions in children presenting with SRNS at our institution.Methods. e study was conducted at Sardar Vallabh Bhai Patel Postgraduate . All children aged 1 -14 years presenting with primary SRNS and in whom renal biopsies were performed were included in the study. eir demographic, clinical, laboratory and histopathological data were retrieved from les and original renal biopsy forms. Results. A total of 40 children had a clinical diagnosis of SRNS; 23 were males and 17 females (male:female ratio 1:35). eir mean age (± standard deviation) was 4.47 (±2.98) years (range 1 -14 years). e histopathological lesions seen on renal biopsy specimens comprised minimal-change disease (MCD) (n=18), focal segmental glomerulosclerosis (FSGS) (n=12), immunoglobulin A nephropathy (IgAN) (n=5), immunoglobulin M nephropathy (n=2), membranous nephropathy (n=2) and idiopathic mesangial proliferative glomerulonephritis (n=1). Conclusion. MCD is the predominant lesion in children with SRNS at our institution, followed by FSGS and IgAN.S Afr J CH 2013;7(4):153-154.

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