Clinic and epidemiologic characteristics in the with squamous cell carcinoma of the mouth and oropharynxResumo / Summary O câncer de boca e orofaringe é de comportamento agressivo e, no Brasil, a incidência é considerada uma das mais altas do mundo, sendo o mais comum da região de cabeça e pescoço. Objetivo: O objetivo deste trabalho é analisar os aspectos clínico-epidemiológicos dos pacientes e a evolução da doença. Costa. This was analyzed with emphasis on age, gender, profession, ethnic aspects, tobacco and alcohol use, dental prosthesis, referement origin, site of the lesion, clinical staging, histologic grade, treatment methods, survival and second cancer presence in the study group. The data were analysed by Exact Test of Fischer. Results: In the oral cavity cancer patients, a male female ratio of 3.35:1 was observed, the median age was 62 years (ranging 46 to 91 years), 90.7% were Caucasian, 81% were referred from medical professionals, tobacco use was identified in 76.8%, alcohol intake in 74%, 79% were not dental prosthesis users, tongue was the commonest site identified (51.1%), 53% were staged as III and IV clinical stages, 72.1% were moderately differentiated SCC, combined modality of treatment (surgery and adjuvant radiation therapy) was employed in 47% and 9.3% presented a second primary tumor. For the oropharynx, the male female ratio was 11.5:1, the median age was 58 years (ranging 40 to 81 years), 92% were Caucasian, 92% were referred from medical professionals, exposure to tobacco and alcohol was respectively noted in 84% and 80%, 52% did not use dental prosthesis, the tonsils were the commonest site (76%), 96% were staged as III and IV, 84% had moderately differentiated SCC, 75% underwent combined treatment (surgery and adjuvant radiation therapy) and 8% presented a second tumor elsewhere. There was not significant relationship between the clinical staging and tobacco, alcohol and dental prosthesis exposure. These factors, the age and the histologic grade had no relationship with the tumor site. For the oral cavity, 69,7% were alive with no evidence of disease and for the oropharynx, 22% were under this condition. Conclusion: The professional who performs the first evaluation is important in recognizing the lesions in order to achieve early detection.Palavras-chave: carcinoma espinocelular, câncer bucal, boca, orofaringe, epidemiologia.

A therapeutic decision in the treatment of Tis/T1a glottic carcinoma with radiotherapy (RT) or transoral laser surgery (TOS) is still an open issue. Oncologic outcome and voice quality may support the choice for the latter To conduct a systematic review and meta-analysis to compare oncologic and functional outcomes of TOS and RT as treatment options for Tis/T1a glottic cancer. Literature research on online databases was carried out. Potentially eligible articles were reviewed. Relevant articles were selected and evaluated. There was statistical significance favoring patients initially treated with TOS when it comes to overall survival, disease-specific survival and larynx preservation. No difference in local control was found. TMF, Jitter and Shimmmer measurements presented statistically significant results in favor of RT. Self-assessment of voice quality (VHI) and f0 showed no statistically significant differences. Maximum Phonation Time (MPT) had a better response to RT. There is a trend in favor of RT. Tis/T1a glottic cancer patients submitted to TOS had significant overall and disease specific survival and had fewer risks of having a total laryngectomy, when compared to the radiotherapy group. The self-assessment of voice quality and f0 did not show any difference; however, Jitter, Shimmer and MPT measurements favored radiotherapy.

Prophylactic use of PMMF decreases the incidence of pharyngocutaneous fistula after salvage total laryngectomy. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2317-E2321, 2016.

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Most head and neck tumors are diagnosed at advanced stages, due to patient and health care factors.