Plants are often used as herbal medicines because their active substances have known. Mangrove as herbal medicines are still under-researched; mangrove leafextract can be useful as anti-inflammatory, antibiotic, hemolytic drug, hypoglycemic has been specifically investigated for its inhibitory power againstStaphylococcus aureus as one of the causes of angular cheilitis and shows good results. This true experimental laboratory research with a posttest only control group design used 24 male white rats of the Wistar strain which were divided into group-1 were induced with S.aureus and given mangrove leaf extract, thegroup-2 was induced with S.aureus and given gentamicin, the group-3 was induced with C.albicans and given mangrove leaf extract, and the group-4 was induced with C.albicans and given miconazole. On the third day, wound length in the first group-1 was 0.23±0.2, in the group-2 was 0.00±0.0, in the group-3was 0.21±0.2, and the group-4 was 0.16±0.2. Based on the Friedman test, it showed significant results (p<0.05). It was concluded that mangrove leaf extract accelerated the wound closure process of angular cheilitis induced by S.aureus and C.albicans.
Abstract-Acute (primary) herpetic gingivostomatitis (AHGS) is the most common form of HSV-1 infection in the oral cavity. These infections are reported mostly in children, usually localized and asymptomatic but in adult patients and immunocompromised conditions tend to be more severe, last longer, and can lead to systemic viremia. Case: A 46-year-old male patient came to RSGM FKG UI with a complaint of painful sore mouth, especially on the tongue since 5 days ago with previous history of fever. Patients feel pain around the head and while swallowing. On the examination, there were multiple ulcers at the gingival margin, interdental papillae, mucobuccofold, lateral of tongue, and also marginal gingivitis. Based on anamnesis, clinical and laboratory examination, he was diagnosed with AHGS. Case Management: He was prescribed chlorhexidine gluconate 0.2% mouthwash and multivitamin. He was advised to increase fluid intake, nutritious food, adequate rest to minimize the duration and the severity of symptoms. He was also instructed to improve the oral hygiene and encouraged to restrict direct contact to prevent transmission. Complete healing was seen in the next visit. Conclusion: Acute (primary) herpetic gingivostomatitis can be found in all age groups, including adult and elders. Clinical features of multiple ulcers and erythematous of gingival margins can be a pathognomonic sign of this condition. Primary HSV-1 infection usually manifests in the oral cavity so it is important for the dentist to recognize the disease to prevent misdiagnosis and provide appropriate management to the patient.
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