A toxoplasmose é uma zoonose cosmopolita causada pelo protozoário Toxoplasma gondii, podendo acometer mamíferos e aves. O presente estudo teve como objetivo estimar a prevalência do Toxoplasma gondii em avestruzes (Struthio camelus) de criatórios comerciais do estado de São Paulo, como forma de auxiliar no conhecimento do comportamento e importância do parasito nesta espécie animal. Foram colhidas 195 amostras de soro de avestruzes, provenientes de Sorocaba, Campinas, São Carlos, Araçatuba, São Paulo, Vale do Ribeira, Botucatu e São José do Rio Preto, estado de São Paulo. As amostras foram analisadas pela Técnica de Aglutinação Direta Modificada (MAT), para a pesquisa de anticorpos anti - Toxoplasma gondii. Os exames sorológicos revelaram 14,36% de animais sororreagentes ao T. gondii. A titulação mínima considerada foi a diluição maior ou igual a 1:16, e a maior diluição encontrada foi 1:16384. Não foi constatada diferença significativa entre os sexos. Apenas duas regiões (São Paulo e São José do Rio Preto) não apresentaram animais sororreagentes. Esses resultados salientam a importância de um estudo mais aprofundado sobre a infecção em avestruzes, e também sobre as práticas de manejo que venham a minimizar o risco de transmissão da toxoplasmose para essas aves e, por conseqüência, para o consumidor final.
OBJECTIVES: The autoimmune hemolytic anemia (AIHA) is a group of diseases characterized by the presence of autoantibodies that bind to erythrocytes reducing the half-life of these cells. It is a rare condition that occurs in about 1-3 cases per 100,000 children per year, more common in males in ratio of 2:1 cases. This study aimed to obtain the clinical and epidemiological profile of pediatric patients diagnosed with autoimmune hemolytic anemia (AIHA), treated at the reference outpatient clinic. METHODS: Participated in the study through analysis of medical records and completion of the research protocol 24 children with AIHA attended at the reference outpatient clinic between 2009 and 2019, age from 0 to 18 years. Clinical, laboratory and outcome data were obtained from patients records. RESULTS: The results showed that most of the children are female (58%), receive early diagnosis until 2 years of age (58%). The direct antiglobulin test was positive in over 95% of cases. The patients presented cutaneous-mucous pallor (50%) as the initial symptom. However, the limitations inherent in the study, which had a small sample due to the rarity of the disease, should be evaluated. CONCLUSION: The diagnosis of AIHA must be made early, based on a detailed clinical history, suspected by the pediatrician through the characteristic signs of hemolysis and initiated treatment with corticotherapy, which shows high rates of remission and cure of the pathology.
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