The issue of this study refers to the organic production (concentration of carbohydrates, antocyanins and organic acids) intobacco (Nicotiana tabacum L.) from the crop 2008 of two oriental types: PRILEP (P-156) and JAKA (Jv-125/3). The plants were cultivated in controlled experimental conditions in the Botanic garden of Department of Botany, Institute of Biology, Faculty of Natural Sciences and Mathematics-Skopje. Material is treated with heavy metals, applicated in four different concentrations: copper, cadmium, lead and fungicide Ridomil gold. Analyses were made on the first insertion, also named as a phase of lower leaves. Protective antioxidative answer was examined (content of antocyanins). The results show the organic production in tobacco culture (content of carbohydrates and organic acids), which directly reflects the quality characteristics of fermented tobacco and changes physical as well as tasteable performances of tobacco raw material. Conclusions affirmed that noticeable dysfunctions in secondary metabolism were caused, as a result of toxicological effect of heavy metals.
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