Cancer is a leading cause of death worldwide. Although advances have taken place, mainly in relation to diagnosis, care, and preventive tools, the number of cases has been increasing. Plants are important sources of secondary metabolites, such as antimicrobial, antihypertensive, anti-inflammatory, and anticancer compounds. Several studies have revealed that bioactive compounds from plants have proven to have potential anti-cancer activity against a wide range of cancer cells, being considered a rich source of natural compounds with anti-cancer properties. Bioactive compounds from plants can interact with all biological systems currently identified as responsible for tumor development. Furthermore, these compounds can act by inducing cell death through the process of apoptosis, autophagy, and necrosis, which in turn regulate the metabolic networks of cells against uncontrolled cell division. The purpose of this chapter is to discuss the main classes of bioactive compounds, the beneficial effect of these compounds in primary cancer prevention, and their potential mechanisms of action.
A utilidade prática, aspectos positivos e desvantagens são mostrados nesta mini-revisão por meio da apresentação de uma fórmula prática para se calcular as dosagens de sanitizantes clorados (SC), a qual fornece a quantidade de cloro a ser utilizada na solução em grama (g) ou mililitros (ml) e duas figuras i) as concentrações cloradas já calculadas para locais que manipulam ou que processam alimentos e ii) com as vantagens e desvantagens dos SC. Os SC são muito utilizados no setor da agroindústria no mundo todo, no entanto, produzem cloramina, substância tóxica, cancerígena aos seres humanos. Alternativas ao uso do cloro se fazem necessárias como o ozônio (O3), peróxido de hidrogênio (H2O2), ácido peracético (CH3CO3H), raios ultravioletas com comprimento de onda de 250 a 275nm por apresentarem atividade germicida. Estudos são necessários para diminuir o custo de aplicação destas tecnologias nas empresas. The practical utility, positive aspects and disadvantages are shown in this mini-review by means a practical formula to calculate the dosage of chlorine sanitizers (CS), which provides the amount of chlorine being used in the solution in gram (g) or milliliters (ml) and two figuras i) concentrations as calculated for chlorinated sites that handle or process food and ii) the advantages and disadvantages of the CS. The CS are widely used in the agribusiness sector widely used in the agribusiness sector worldwide, however, produce chloramine, toxic, carcinogenic to humans. Alternatives to the use of chlorine are needed such as ozone (O3), hydrogen peroxide (H2O2), peroxyacetic acid or peracetic (CH3CO3H), ultraviolet rays with a wavelength of 250 to 275nm by presenting germicidal activity. Studies are needed to reduce the cost of implementing these technologies in business.
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