No abstract

Hydroboration of alkynes is of special interest to researchers since it is the most straightforward process for the synthesis of highly important vinylborane synthetic intermediate compounds. It is significant in terms of both regioselectivity and stereoselectivity, since several positional isomers are formed during the process of hydroboration. Given the importance of this class of compounds, an extensive study has been carried out regarding catalytic condition development and detailed mechanistic studies for selectively obtaining a single isomer. This review comprehensively summarizes both the regioselective and stereoselective catalytic hydroboration of alkynes. It is aimed at giving readers accurate knowledge of the catalytic systems available for the hydroboration of certain alkynes. We anticipate that this inclusive review will encourage researchers to explore more new types of catalytic systems to achieve the remarkable process of hydroboration of alkynes.

Organoboranes obtained from hydroboration reactions are one of the important classes of compounds that could be used to provide valuable synthons for follow-up transformations such as various functional group incorporation...

C−F bond activation is currently considered to be "a hot topic" in many different but interconnected fields of research, due to its inherent inertness and unique properties. While considerable progress has been made in this particular field of research, activating strong bonds, such as the C−F bond, continues to be a challenge. Because polyfluorinated compounds are commercially available, the functionalization of C−F bonds has been extensively studied for preparing partially fluorinated compounds, some of which are biologically active and are used as functionalized materials. However, chemo-and regioselective methods are still required to prepare useful partially fluorinated compounds. In addition, a new strategy for the activation of a C−F bond in less reactive monofluorinated compounds remains a need. Directed strategies have been extensively used in C−H bond activation chemistry to achieve high efficiency as well as a high regioselectivity. On the other hand, a directed strategy that is applicable to the activation of various unreactive bonds, such as C−O, C−N, C−F, and others is still needed, compared with directed C−H bond activation. In this Review, we focus on the directed strategy for the activation of inert C−F bonds.

Convenient, easily handled, laboratory friendly, robust approaches to afford synthetically important organoboron compounds are currently of great interest to researchers. Among the various available strategies, a metal-free approach would be...