Background: Community acquired pneumonia (CAP) is an infection affecting a significant proportion of population from all age groups across the globe with considerable morbidity and mortality. There is a need for data from various parts of India to better understand the epidemiology of CAP. Present study is an attempt to present the relevant data from a tertiary care hospital in Rajkot, Gujarat during the study period.Methods: This observational prospective descriptive study was done during November 2014 to April 2016 at Department of TB and chest diseases, PDU Hospital at Rajkot in Gujarat. 50 patients with clinical features suggestive of CAP were enrolled. Male and female patients (above age of 12 years) admitted to TB and Chest ward or patients on OPD basis were selected for the study. The diagnosis of CAP was mainly clinical with some assistance from radiological picture. All patients were thoroughly examined particularly with regards to detailed history, clinical examination, predisposing factors and associated co-morbid conditions. Sputum examination-gram stain and culture sensitivity was done in all patients, where sputum was available. Sputum examination for acid fast bacilli (AFB) by Ziehl Nelson staining technique was done. Age and sex distribution of patients, microorganisms isolated and the clinical features were described and analyzed.Results: The mean age was 38.38±17.41 (SD) years. Male patients were 34 (68%) and female patients were 16 (32%). Male to female ratio was 2.1:1. In this study, 47 (94%) patients were admitted in the hospital for the management and 3 (6%) patients were treated on the OPD basis. Fever and cough were most common symptoms whereas dull note on affected side and crepitations were the commonest signs elicited. In this study, the most common predisposing factor was smoking which accounted for 20 (40%) patients. The most common lobe involved was Left Lower lobe accounting for 20 (40%) patients and least common lobe involved was left upper lobe accounting for 2 (4%) patients. Streptococcus pneumoniae was the most common organism isolated in 8 (16%) patients and second common organism was Klebsiella isolated in 7 (14%) patients.Conclusions: Males, especially smokers were more commonly affected and Streptococcus pneumoniae was the most common organism isolated. The study gives the hospital based data from the region regarding epidemiology and clinical features of community acquired pneumonia.
Background: Lower Respiratory Tract infections are responsible for one-fifth of the deaths caused due to infectious diseases in India and Pneumonia is a major culprit. Timely and appropriate empirical treatment based on knowledge of local etiological factors is important in the management of the disease. Data related to investigation profile and therapy as well as morbidity and mortality is available from different geographic regions. Present study describes the management and outcome of disease data from a tertiary hospital at Rajkot in Gujarat state during the study period. Methods: The present prospective observational study was completed in the study duration (November 2014 to April 2016) at tuberculosis and chest diseases Department of PDU Hospital at Rajkot, Gujarat. 50 patients above 12 years of age with CAP on clinical diagnosis assisted by radiology were included in the study. The haematology profile, therapy, complications and mortality were described. Results: Haemoglobin was below 10gm percent in 22% cases. Leucocytosis was observed in 72% cases. Ten percent patients were seropositive for HIV. There was a moderate response to treatment with penicillin group of drugs (approximately 22%). Many patients had to be offered other group of drugs like Cephalosporins, macrolides and quinolones for clinical response. Most common complications observed were: Delayed resolution in 12 (24%) patients, synpneumonic effusion in 6 (12%) and septicaemia in 3 (6%) patients. Mortality rate was 6% during the study period. Conclusions:The results indicate a low response to treatment by penicillin group antibiotics and a high rate of complications. Mortality is similar to reports from India.
Word counts of main text: 740 (excluding the references, tables),
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.