Introduction: Acacia nilotica is otherwise called Babul is multipurpose nitrogen fixing tree legume. Its roots are beneficial in treating tumors, cancer, and tuberculosis. One of the most consumed beverages in the world, green tea (Camellia sinensis) has been researched for its potential health benefits in treating conditions like cancer, diabetes, obesity, heart disease, and neurological illnesses. The aim of this present study is to assess the combined effects of green tea and babul herbal formulation as an anti-inflammatory agent. Materials and Methods: Green tea and Babul extract was prepared. Albumin denaturation assay and egg albumin denaturation assay were used to assess the anti-inflammatory activity. Results: Both assays showed that Green tea and babul extract was effective in inhibiting the albumin denaturation at different concentrations. Conclusion: We conclude that green tea and babul herbal formulation can be a potent anti-inflammatory agent.
A pregnant woman is exposed to so many environmental influences that it may be tough to pinpoint just one that may affect her pregnancy. In today's technology driven world, everyone relies on their cell phone to stay in touch with friends and family, get their work done, keep track of what's going on around them.Widespread concerns have been raised about exposure to electromagnetic fields from sources used for mobile telecommunication. Indeed, mobile phone use has increased considerably along with reducing its costs, and developing countries are establishing mobile telecommunications rather than the more expensive fixed-line systems. Exposure to radio frequency electromagnetic field (RF-EMF) during pregnancy could affect the growth and development of the foetus and the duration of pregnancy , either directly due to radiation of the foetus and placenta or indirectly as a result of altered maternal physiology. A questionnaire based survey was conducted among 100 women to analyse their awareness, exposure time on gadgets etc and the results were analysed. Most of the women are not aware of the effects of radiation, the amount of radiation they are exposed to and also specific absorption rate (SAR) value. Women need more awareness about the usage of gadgets, time limits, radiation etc which can be achieved through health education.The aim of the study is to create awareness on the effects of radiation emitted from electronic gadgets during pregnancy among women.
Aim: To assess the anti proliferative efficacy of Centella asiatica queoues leaf extract on human lung cancer cell line Introduction: Centella asiatica (family Apiaceae), commonly known as Indian Pennywort, is an ethnomedical plant that is widely used in India for treating skin problems and for revitalizing the brain and nervous system. It has been reported to have various pharmacological activities, including antioxidant, anti-inflammatory, anticancer, neuroprotective, cardioprotective, skin protective, radioprotective, immunomodulatory, memory-enhancing, and wound-healing properties. Asiatic acid and its derivatives possess a broad spectrum of pharmacological activities, such as anticancer, wound healing, anti-inflammatory, antidiabetic ,hepatoprotective and neuroprotective activities. The aim of the study is to assess the antiproliferative efficacy of Centella asiatica queoues leaf extract on human lung cancer cell line. Materials AND Methods: Human lung adenocarcinoma-A549 cell line was procured from National Centre for Cell Science (NCCS, Pune), India. The effect of Centella asiatica on cell viability was measured by MTT assay following the method by Mosmann Briefly, the cells (1 × 105 cells per ml) were seeded in a 96 well micro titre plate (100 μl per well) with replications. Treatment was conducted for 24 with different concentrations (50,100,150,200,250 and 300 μM) of Centella asiatica .After incubation, 20 μl of 5 mg/ml MTT stock solution was added to each well and incubated for 4 h at 37 °C. The obtained formazan crystals were solubilized with DMSO and the absorbance was measured at 570 nm using a microplate reader (SpectraMax M5, Molecular Devices, USA). Cell viability (%) has been shown as a ratio of absorbance (A570) in treated cells to absorbance in control cells (0.1 % DMSO) (A570). The IC50 was calculated as the concentration of sample needed to reduce 50 % of the absorbance in comparison to the DMSO-treated control. Percent cell viability was calculated following the equation: Cell viability (%) = {A570od of ( sample)/A570 od of (control)} x 100 Results and Discussion: Results show that centella asiatica has an antiproliferative effect on human lung cancer cell line. The characterisation of morphological changes in human lung cancer cells treated with Centella asiatica leaf extract compared to their respective controls were observed under phase contrast microscope.Visible destruction of the cancer cells were observed at the initial concentration of 25 microgram/ml. Further concentrations however showed increased antiproliferative activity proving it to be a potent anticancer drug. Conclusion: This research concludes that centella asiatica leaf extract has a potent antiproliferative effect on human lung cancer cell lines.However further research is needed to understand the mechanisms of cytotoxicity of the plants.
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