This is a partial analysis of the outcome of a survey looking at user perception of the institutional use of Complementary and Alternative Medicine (CAM) in Florianópolis healthcare centers. Structured interviews were applied to users treated with CAM in the locations offering this option most often, using data-based theory as a theoretical-methodological reference. For the most part, the use of CAM was proposed by basic health professionals (the operators of biomedical care), initially as a preferred alternative to biomedicine. Interviewees preferred CAM, associating it to fewer side-effects. Users mentioned enhanced dialog with professionals to negotiate treatment forms. The hypothesis emerged that CAM could be the initial treatment option in a large number of cases, saving conventional treatment for subsequent use if necessary, or in some cases as the single or complementary treatment. This enables drafting an expanded flow using CAMs in primary healthcare. New studies and institutional experience are required to investigate this hypothesis, expanding the use of CAM in an ecology of institutional care.
Chromatography Iridoids K562 and Nalm6 cells Plumericin A B S T R A C T The aim of this research was to evaluate the fractions obtained from the leaf, stem and roots of Allamanda schottii, Pohl, Apocynaceae, responsible for the cytotoxicity, using several cell lines. Cytotoxicity was correlated with the season the part of the plant, and the major compounds were assessed. The ethanol extracts of leaves, stems and roots obtained at different seasons were evaluated in the human erythromyeloblastoid leukemia cell line (K562). Subsequently the ethanol extracts and dichloromethane fractions collected in winter were evaluated in mouse fibroblast cell line (Mus musculus) (L929), cervix adenocarcinoma (HeLa), human pre-B leukemia (Nalm6), as well as K562 cell line. The compounds plumericin, plumieride and ursolic acid isolated from ethanol extracts of the stems were evaluated in the same cell lines, as well as on breast adenocarcinoma cell line (MCF-7), and Mus musculus skin melanoma cell line (B16F10). The chromatographic profiles of the dichloromethane fractions were obtained by high performance liquid chromatography. The results revealed that the season during which A. schottii was collected, and the part of the plant analyzed, influence the cytotoxicity on the K562 cells tested. On the other hand the dichloromethane fractions, mainly from the stems and roots, are responsible for the cytoxicity on the cells tested. These results may be associated with the seasonal variation of plumericin in these parts of the plant. This information is in accordance with the HPLC analysis. The resultsclearly show the potential for the phytotherapeutic use of this species, and suggest that the cytotoxic activity observed may be due to the presence of plumericin, or to minor com-pounds not yet identified. The seasonal influence on the production of secondary metabolites was verified.
Este artigo tem por objetivo investigar como o tema saúde de imigrantes haitianos vem sendo abordado em estudos empíricos qualitativos. Realizou-se revisão sistemática nas bases de dados PubMed, Scielo, Scopus e Web of Science, entre 2007 e 2019. Esta revisão orientou-se por princípios da revisão sistemática quantitativa, aplicados à pesquisa qualitativa. Os 17 artigos selecionados foram revisados criticamente e os dados relevantes extraídos e sintetizados utilizando-se preceitos da síntese temática. Os resultados apontam que percepções e saberes sobre saúde e doença estiveram presentes em todos os trabalhos. Os estudos incluídos demonstram motivos pelos quais os participantes não acessam serviços de saúde, no entanto, não exploram como ocorrem as trajetórias de cuidado. Recomenda-se que trabalhos futuros reconheçam a necessidade do diálogo intercultural, avançando no sentido de compreender a lógica e os significados que dão sustentação às representações socioculturais do cuidado à saúde.
Resumo: A dimensão simbólica do processo saúde/enfermidade/atenção está presente na representação das enfermidades de forma diferente em cada grupo social. Nesta representação, a conceituação etiológica e as estratégias de cura podem incluir uma multiplicidade de saberes, as quais orientam o percurso terapêutico do paciente. O modelo explicativo utilizado pela comunidade de Kaydesa, Haiti, revela uma série de símbolos e construções culturais envolvidos na aflição e na enfermidade, onde salienta-se a influência das perspectivas psicossociais neste processo e o legado histórico da violência estrutural. Este artigo pretende lançar luz acerca dos aspectos subjetivos do processo saúde/enfermidade/atenção e sob este prisma refletir proposições teóricas sobre a ação placebo e nocebo mediada pela cultura vodou, bem como a postura da medicina oficial frente a estes conceitos no contexto sócio econômico local. Conclusão: a partir das reflexões é possível reconhecer a conexão existente entre o efeito placebo e nocebo no processo saúde/enfermidade/atenção e identificar a influência da violência estrutural no âmbito da saúde pública em Kaydesa, a qual manifesta-se interferindo na representação das doenças e nas práticas em saúde dos moradores locais.
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