The number of Diabetes Mellitus (DM) patients has been increasing. Several risk factors linked with Type 2 DM are overweight, lack of exercises and an unhealthy diet. The level of zinc serum DM patients is also lower than that of non DM and this is associated with poor blood glucose control. The research objective is to reveal the correlation between BMI (Body Mass Index), physical activity, level of zinc serum with level of fasting blood glucose on Type 2 DM. The research used a cross sectional design. The study sample was 34 Type 2 DM patients in 3 health centers in the city of Surabaya that were taken by consecutive sampling method. The Rank-Sprearman correlation test analysis revealed that there were correlations between physical activities (p = 0,001, r=-0,592), zinc serum levels (p=0,050, r=-0,339) with fasting blood glucose, and that there were no correlations between BMI (p=0,680, r=-0,073) and fasting blood glucose levels. It was concluded that the research revealed that there were correlations between physical activities, zinc serum, and fasting blood glucose, and that there were no correlations between BMI and fasting blood glucose of Type 2 DM patients.
Background: Patients with Diabetes Mellitus (DM) Type 2 are at risk of micronutrient loss related to metabolic diseases, one of them is zinc. It plays an important role since it affects the function of pancreatic cell β, insulin activities, glucose homeostasis and pathogenesis of DM. Low zinc levels are associated with higher complications of DM. One of the nutrients that helps absorbing zinc is organic acids such as citric acid and ascorbic acid contained in citrus fruits.Objective: to analyze the effect of citrus fruits (Citrus reticulata) and zinc supplements consumption on fasting blood glucose in women with DM Type 2.Method: This study was an experimental study using pretest and posttest method with control group. The subjects were 30 people with DM Type 2 in Prolanis club in three Puskesmas in Surabaya who had been selected using consecutive sampling, and divided into 2 groups, namely the treatment group that consumed 200 g of orange and 20 mg of zinc supplement per day and the control group that consumed only 20 mg zinc per day. Citrus fruits and zinc supplements were consumed daily for four weeks. Fasting blood glucose was analyzed using automatic chemistry analyzer. Data analysis included univariate analysis with Shapiro-Wilk and bivariate analysis with Independent t-test, Mann-Whitney and Paired t-testResults: Fasting blood glucose in the subjects consuming citrus fruits and zinc supplements was decreased by 16.67 mg/dl (from 155.87 mg/dl to 139.20 mg/dl) (p = 0.121), while the group with zinc consumption was decreased by 9.85 mg/dl (from 140.93 mg/dl to 131.13 mg/dl) (p = 0.095). The decrease in fasting blood glucose in both groups was not statistically significant.Conclusion: Consumption of citrus fruits and zinc supplements did not significantly reduce fasting blood glucose in women with DM Type 2. Further research is needed with a longer period of intervention to better reflect the changes in zinc metabolism related to blood glucose control.ABSTRAKLatar Belakang : Pasien Diabetes Mellitus (DM) Tipe 2 beresiko kehilangan zat gizi mikro terkait metabolik penyakitnya, salah satunya adalah zinc. Zinc berperan penting karena mempengaruhi fungsi sel β pankreas, aktifitas insulin, homeostasis glukosa dan patogenesis DM. Kadar zinc yang rendah terkait dengan komplikasi DM yang lebih tinggi. Salah satu zat gizi yang membantu penyerapan zinc adalah asam organik seperti asam sitrat dan asam askorbat yang terkandung dalam buah jeruk.Tujuan : Menganalisa pengaruh konsumsi buah jeruk (Citrus reticulata) dan suplementasi zinc terhadap kadar gula darah puasa wanita DM tipe 2.Metode : Rancangan berupa quasi eksperimental dengan metode pretest and posttest with control group. Jumlah subjek 30 orang wanita DM tipe 2 anggota klub Prolanis di 3 Puskesmas di Kota Surabaya yang dipilih secara consecutive sampling, terbagi dalam 2 kelompok yaitu kelompok perlakuan yang mengkonsumsi 200 gram jeruk dan suplementasi zinc 20 mg/hari serta kelompok kontrol hanya mengkonsumsi zinc 20 mg/hari. Intervensi dilakukan 4 minggu. Gula darah puasa dianalisa menggunakan automatic chemistry analizer. Analisis data meliputi univariat dengan Shapiro-Wilk, analisa bivariat meliputi Independent t-test dan Mann-Whitney.Hasil : Meskipun rata-rata penurunan gula darah puasa sebesar 16,67 mg/dl pada subjek yang mengkonsumsi jeruk dan suplementasi zinc (p=0,121), namun tidak signifikan secara statistik.Kesimpulan : Konsumsi buah jeruk dan suplementasi zinc tidak signifikan menurunkan gula darah puasa wanita DM Tipe 2. Diperlukan penelitian lanjutan dengan jangka waktu intervensi yang lebih lama.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.