Conclusions: Statistically significant variations were observed from baseline to clinical-pathological characteristics in HCV vs HBV associated HCC. Our study suggests prompt and early screening for high risk patients so that the rate of progression of these chronic viral diseases to cirrhosis and cancer can be decreased.
Systemic sclerosis is a multisystem disease featured with autoimmunity and organ fibrosis. Although gastrointestinal (GI) tract involvement is common in patients with systemic sclerosis, colonic perforation is extremely rare. Benign pneumatosis intestinalis, a phenomenon more frequently seen in rheumatologic conditions, makes the diagnosis of colonic perforation even more challenging. We report a unique case of colonic perforation in a patient with chronic systemic sclerosis. This patient initially presented with mild abdominal pain and hematemesis. Urgent upper endoscopy was unremarkable and radiology showed stable pneumatosis intestinalis. Due to worsening abdominal pain, laparotomy exploration was performed and colonic perforation with transmural ischemic necrosis was found.
Hemolytic uremic syndrome (HUS) is the triad of nonimmune (Coombs negative) hemolytic anemia, low platelet count, and renal impairment. HUS has been associated with a variety of gastrointestinal malignancies and chemotherapeutic agents. We present a patient with pancreatic cancer treated with gemcitabine for palliation who developed gemcitabine‐induced HUS (GiHUS) which responded to some extent to blood and platelet transfusions. With the increase in the use of gemcitabine therapy for pancreatic and other malignancies, it is essential to accurately and timely diagnose GiHUS to avoid the life-threatening complications.
Objective: To compare the angiographic findings in patients with acutemyocardial infarction (AMI) and compare it with diabetic and non-diabetic patients admittedin the cardiology department of LUHMS. Study Design: Descriptive analytical study. Setting:Department of cardiology at Liaquat University of Medical and Health Sciences (LUMHS)Hospital, Hyderabad. Period: Periods of 1st June 2012 to 31st July 2013. Patients & methods:All patients with AMI and had diabetes mellitus and age eighteen or more than eighteen yearsboth male and female were included after taking informed consent. Results: Out of 297 patientsdiagnosed as AMI, 195 (65.65%) patients had acute ST elevation Myocardial Infarction and 102(34.35%) patients had acute non ST elevation myocardial infarction. Among 297 patients, 190(64%) patients were non-diabetic and 107 (36%) patients were diabetic. Diabetic patients wereolder, more often males, but prevalence of smoking was less marked. Coronary angiographicfindings among patients with AMI and diabetics revealed three vessels disease. Conclusion:Older patients with male predominance presented with AMI and had diabetes mellitus werefound to have three vessels disease in coronary angiography.
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