Rectal cancer treated with neo-adjuvant therapy and radical resection with TME for better local control may be associated with greater anastomotic complications particularly when a good pathological response is seen.

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During the nineteenth century, when the incidence of and the mortality from pulmonary tuberculosis were much greater than at present, a large percentage of sufferers from diabetes mellitus died of coma, and most of those who survived this died of pulmonary tuberculosis. Publications towards the end of that century indicate that 50% of diabetics succumbed to pulmonary tuberculosis. For example, Windle (1883) Table I.