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In spite of numerous results found in literature, the albumin and globulin content of serum in health and disease has been reinvestigated by use of Robertson's1 method, because of the simplicity and freedom from possible error of the new technic as compared with that of former methods. The small amount of serum used is another advantage and has made possible the use of two controls on each serum examined by the writer. The results which can be obtained are uniform, especially if the writer's suggestions about the technic, which will soon be published, are followed and his automatic pipet2 is used to assure accuracy of measurements.During the last seven months a number of normal serums have been examined. The average results differ slightly from those obtained by Robertson's method previously reported.3 The total protein is lower than in the previous series, due to the fact that serums were taken, except in a few cases, from patients who were confined to bed as a result of a fracture or uncomplicated herniotomy, or from those who had been lying down for twenty-five or more minutes. The non\x=req-\ proteins are slightly higher, while the percentage of globulin in the total protein is moderately increased. The last four serums were taken from the same person at different times throughout a period of six months. The values are quite uniform (Table 3). LITERATUREThe literature contains many results for the normal value of serum proteins, most of which will be found in Table 1. Several of the average values were taken directly from the articles by Erben.4 Com-