Dandy-Walker syndrome (DWS) is a rare brain malformation involving the cerebellum, and the fluid filled spaces around it, usually detected during the antenatal period or the early infancy. Clinically, it is characterized by mental retardation, developmental delay as well as cerebellar ataxia. It has been frequently associated with other conditions such as congenital heart diseases, primary hypothyroidism, and other disorders of the central nervous, gastrointestinal, genitourinary, and orthopedic systems. In this report, we describe a 3-month-old Saudi boy with the rare association of DWS with central diabetes insipidus, congenital central hypothyroidism, and type-2 renal tubular acidosis.
Objective: We aimed to investigate the clinical manifestations and associations of acquired hypothyroidism in children at King Abdul-Aziz University Hospital (KAUH) in the western region of Saudi Arabia.Methods: A retrospective descriptive study was conducted in Jeddah, Saudi Arabia from January 2010 to January 2015. The study included 265 children aged between one and 18 years old with a confirmed diagnosis of acquired hypothyroidism who attended the pediatric endocrine clinic at KAUH. Data were obtained by reviewing the medical records and laboratory investigations of the patients by using KAUH's "phoenix" system. Results:Of the 265 children diagnosed with acquired hypothyroidism, the commonest clinical presentations were short stature (32.5%), loss of appetite (16.2%), weight gain (13.6%), fatigability (12.1%), constipation (9.8%), cold intolerance (5.3%), and goiter (2.6%). Vitamin D deficiency was the commonest associated disorder (present in 37% of patients) followed by type 1 diabetes mellitus (in 22.3%) and Down syndrome (in 8.3%). Conclusion:Isolated short stature was the most common presentation of acquired hypothyroidism. Pediatricians should be aware of the need to screen children who present with short stature for hypothyroidism. Vitamin D deficiency was the commonest disorder associated with acquired hypothyroidism. In our setting, vitamin D supplementation would be beneficial as a preventive measure. thyroid hormone will help to restore normal sexual development and high velocity. The aim of present study was to investigate the clinical manifestations and associations of acquired hypothyroidism in children and adolescents at King Abdul-Aziz University Hospital (KAUH) in the western region of Saudi Arabia. Methods Study setting and participantsA retrospective descriptive study was conducted to review the clinical presentation and associated disorders of acquired hypothyroidism. Data collection took place at King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia. The population was 265 children and adolescents aged one to 18 years at the time of diagnosis.The data was obtained by reviewing the medical records of children and adolescents with acquired hypothyroidism that was being followed up at the pediatric endocrinology clinic at KAUH from January 2010 to Citation: Al-Agha AE, Alshugair RM, Aljunedi WA, Badakhan BA (2016) Clinical Presentation of Acquired Hypothyroidism and Journal of Patient Care
Objective: To assess the advantages and disadvantages of using freestyle libre flash glucose monitoring system (FGMS) in children and adolescent with type 1 Diabetes (T1DM). Methods: A prospective pilot study included 70 children and adolescents with T1DM visiting the pediatric diabetes clinic at King Abdulaziz University hospital (KAUH), Jeddah, Saudi Arabia from June to August, 2016. 26 (37.1%) were males and 44 (62.9%) females, aged from 6-20 years, mean age 12.83 ± 3.2 years. A survey questions were addressing, the advantages, disadvantages and benefits of FGMS with sleeping, daily activities, exercise, accuracy and participants' satisfaction from FGMS. Results: Parents of participants reported 95.7% of easily ability to measured glucose during sleep. 77.1% have given a negative answer about sensors disturbance during exercise. 85.7% did not have any difficulties in wearing or taking off clothes with the sensor. 72.8% denied any pain or itching from the sensor. 75.8% reported that the sensor is well fixed to the skin. 92.2% agreed that FGMS has advantages of facilitating more observation, regulating their glucose variability and adjustments of insulin doses. Conclusion: Majority of children and adolescents with their parents preferred using FGMS to have a painless, easier detection and adjustment of hypoglycemic/hyperglycemic episodes in comparison to the widely traditional used finger sticking glucometers.
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