Purpose To evaluate the effect of corneal density and thickness on the accuracy of tonometry readings obtained via three most used techniques. Method Intraocular pressures of 45 patients’ right eyes were measured using Goldmann Applanation, iCare, and non-contact tonometry methods. Corneal parameters were obtained using the Pentacam Camera System. Data obtained were analyzed using Paired t Test, Pearson’s correlation coefficient, multiple linear regression analysis, and Bland–Altman plots. Results The mean corneal thickness was 545.4 ± 3.93 μm. The mean corneal density of total, stromal, 0–2 mm, and 2–6 mm zones were 27.85 ± 6.23 GSU, 24.61 ± 6.05 GSU, 20.76 ± 2.96 GSU, and 20.81 ± 3.51 GSU respectively. IOP readings had a statistically significant correlation with corneal stromal thickness, as well as with total and stromal density. The stromal density, however, showed higher correlation with the three tonometry methods than did the total density (iCare: − .482 (0.001) stromal density versus− .464 (0.001) total density, NCT: − .376 (0.011) versus − .353 (0.017), GAT: − .306 (0.041) versus − .296 (0.048)). Statistical differences were found in comparing the iCare readings with GAT (P < 0,00) and with NCT (P < 0,00), with mean differences of 1.8 mmHg ± 2.6 and 2.0 mmHg ± 2.6 respectively. GAT and NCT measurements showed no statistical difference (P > 0.05). Conclusion This study shows that both central corneal thickness and stromal density are significant influential factors of reliable IOP readings. It is necessary to consider more corneal biomechanical properties, as well as exercise a high degree of caution in any new attempts towards adjusting an IOP-correction equation.
Purpose: To retrospectively analyze data related to results of different techniques of pterygium surgery performed in the Cornea Service of the Department of Ophthalmology at the Heraklion University Hospital of Crete between the years 1998-2015.Methods: Data from patients that completed at least 10 months of follow up were included in the study. Out of 115 eyes of 110 patients 80 eyes were operated for primary and 35 for recurrent pterygium. The surgical techniques included surgical excision with bare sclera (BSE), with and without the intraoperative 4 minute use of Mitomycin-C 0.02% (BSE+MMC), as well as surgical excision with conjunctival autograft (CAU) or amniotic membrane transplantation (AMT)Results: During the mean follow up of 20+16.3 months, the overall recurrence rate was 9.6% (11 cases). BSE technique resulted in 16.7% recurrence (2 cases) in 12 primary pterygia, while 6 out of 68 primary pterygia (8.8%) recurred after BSE+MMC. Recurrent cases operated with BSE+MMC had 13% recurrence rate (3 out of 23), while none of the eyes that underwent CAU (9 cases) or AMT (3 cases) had another recurrence. Conclusion:The long term results of the current study for different surgical techniques of pterygium excision are in accordance with the literature reports. Authors recommend the use of BSE+MMC for primary and quiet recurrent pterygia cases as being fairly effective, and CAU or AMT for invasive recurrent or even "angry" primary pterygia.
J o u rn al of Cl in ic a l & Ex perim en ta l O p hth almo lo g y
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