Diagnostic technology based on magnetic fields is commonly used in medicine for diagnosis and therapy. However, the exposure to strong electromagnetic fields has adverse outcomes in patients. Thus, the objective of the current study is to investigate the effect of applying external uniform magnetic fields on the blood flow in both healthy and diseased cases of right coronary artery and determine the safe values of the applied magnetic field strengths. The diseased cases include a 40% stenosed artery along with two blood disorder cases with a hematocrit level of 20% and 60%. A comprehensive three-dimensional steady non-Newtonian flow model is developed using the Casson model to investigate the effect of the magnetic field on both shear rate and hematocrits. The model is numerically simulated at different values of magnetic field strengths and its orientation. The results indicated that the magnetic field in the Y-direction has a dominant effect compared to other directions. Moreover, the maximum increase in the main branch mass flow rate fraction is about 6.2%. Another interesting finding is that the wall shear stress is slightly affected by the magnetic field strength. For the stenosed case, it is found that the high magnetic field strengths can reduce the formulation of the vortices and hence reduce the risk of thrombosis, which agrees with published works. Additionally, the obtained results confirm that using a magnetic field up to 11.7 T, which is used in magnetic resonance imaging devices, is safe, and has a slight effect on blood flow parameters such as the wall shear stress.
Numerical simulation of cellular blood flow modeling has attracted many studies in the few recent years due to its importance in determining many macroscopic properties of blood. Additionally, the accurate modeling of blood flow, and hence the diagnosing of many cardiovascular diseases requires a detailed description of the dynamical behavior of individual cells. The aim of this study is to simulate the blood flow in the cellular level to have a better understanding and accurate modeling of blood flow in some cases that are not intensively examined in literature such as the dense suspension of flowing RBCs in microvessel with different degrees of stenosis. The present study is based on an open-source code, Hemocell for modeling blood flow in the cellular level. The lattice Boltzmann method coupled with the immersed boundary method are used to capture the cell deformation and the interaction between plasma forces and cell membrane. The distributions of the RBCs in both radial and axial directions are obtained. The deformation of the cells due to passing through the vessel especially the throat is studied for two cases of stenosis. It is found that the deformation of the cells at the center of the stenosis is higher than the deformation in other regions. Additionally, the increase of the stenosis degree increases the average deformation of the cells. It is observed that a longer time is required for the simulation in the case of 80 % reduction in the diameter.
Numerical simulation of blood flow modeling in cardiovascular system has been one of the most efficient tools in understanding and diagnosing many diseases in the recent few decades. Recent studies have been performed to investigate the effect of the external magnetic fields on the biomagnetic fluids such as blood. There are many applications of magnetic field which are closely related to hemodynamics such as the magnetic resonance imaging (MRI) devices, magnetic drug targeting (MDT) and cell separation. These applications have a direct connection with hemodynamics parameters such as the wall shear stress, pressure drop and recirculation zones. In this study, numerical simulation of blood flow in an abdominal aortic aneurysm under an external magnetic field is performed. Blood is considered as a non-Newtonian fluid with shear-thinning properties, in which the blood viscosity is a function of both shear rate and hematocrits using the Casson model. The three-dimensional axisymmetric flow is considered in the arterial segment. Results at different flow conditions such as the strength of the magnetic field, different inlet velocities and different hematocrits are estimated. The results indicate the significant effect of the magnetic strength on the wall shear stress and the pressure drop which reached 200 % and 600 %, respectively.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.