IntroductionThe Zika virus outbreak in Brazil has had devasting social, medical and financial consequences for families. Both researchers and clinicians are measuring longer-term outcomes to understand the impact of the Zika on child development, functioning and disability. Outcomes and tools used to measure them are very varied and we are unclear how meaningful they are to families and children. This study aimed to identify the parents’ perspectives on relevant areas of functioning and disability that should be included as outcome measures for children with congenital Zika syndrome (CZS), as guided by the International Classification of Functioning, Disability and Health (ICF).MethodsThis qualitative study included parents or caregivers of children aged 0–5 years with confirmed CZS from two states in northeastern Brazil. Interviews were conducted using focus groups. Content mapping followed the WHO’s ICF linking rules. Three raters analysed the content using NVivo V.11.ResultsThirty-two caregivers participated in six focus groups, 88% were mothers with an average age of 30 years. Most children were male (59%) and all were level V (severe) to on the Gross Motor Function Classification System (GMFCS). Overall, 825 themes were mapped to 36 ICF categories. Although parents mentioned areas across all ICF domains, they reported that areas of mobility, eating and recreation were most relevant for them. In addition, environmental factors were highly identified as barriers, specifically services, policies and access to assistive devices. The most predominant facilitators within the environment were; immediate family support, kind relationships with therapists and support from the extended family.ConclusionsAlthough parents emphasised issues related to mobility, their greatest concerns involved environmental factors, such as access and quality of health and social services, systems and policies. These results reinforce the importance of including parents’ perspectives when selecting or developing outcome measures for CZS.
Patients with reflux esophagitis (grade II or III, Savary-Miller, intention-to-treat, n=256, age range 19-82 years) were randomly assigned to a double-blind, double-dummy treatment with either pantoprazole 40 mg once daily or ranitidine 150 mg twice daily. After 4 weeks, each patient was clinically and endoscopically assessed. Failure to heal required a further 4 weeks of treatment and a new evaluation thereafter. After 4 weeks, healing of lesions was confirmed in 63% (69 out of 109) of patients receiving pantoprazole and in 22% (25 out of 113) receiving ranitidine (P < 0.001, per protocol population). After 8 weeks, the cumulative healing rates were 88% and 46%, respectively (P < 0.001). Complete freedom from esophagitis-related symptoms (acid eructation, heartburn, pain while swallowing) was greater in the pantoprazole than in ranitidine group after 2 and 4 weeks (74% vs. 47%; 87% vs. 52%, respectively, P < 0.001). After 4 weeks, the healing rate was 76% in Helicobacter pylori (Hp)-positive vs. 45% in Hp-negative patients treated with pantoprazole (P < 0.01). The Hp status did not influence healing rates in patients treated with ranitidine. The most frequent adverse events in the pantoprazole group were diarrhea and somnolence (2-3% of patients), and in the ranitidine group, headache, diarrhea, dizziness, increase of liver enzymes and pruritus (2-4% of patients). In conclusion, pantoprazole was more effective than ranitidine in the healing rate and relief from reflux esophagitis-associated symptoms, and Hp infection was associated with higher healing rate during therapy with pantoprazole but not with ranitidine.
Prevalencia y factores asociados a la incontinencia urinaria de mujeres mayores RESUMO Objetivo: Verificar a prevalência da queixa de Incontinência Urinária (IU) e os fatores associados em idosas no município de Petrolina/PE. Métodos: Estudo transversal e exploratório realizado em 2009 com 172 idosas nas quais se avaliaram características sociodemográficas, socioeconômicas e estilo de vida. Para investigar a IU utilizou-se o International Consultation on Incontinence Questionnaire-Short Form" (ICIQ-SF) acrescido de questões obstétricas e de comorbidades. Dados trabalhados com intervalo de confiança a 95% utilizando o STATA ® 9.0. Resultados: A queixa de IU esteve presente em 81 (47,1%) idosas. A faixa etária maior que 75 anos de idade estava associada à IU (RP 1,57 IC95% 1,57-11,09). Na associação com ocupação notou-se que tanto as idosas aposentadas (RP 4,64 IC95% 0,98-21,98) quanto as donas de casa (RP 6,25 IC95% 1,14-34,12) tinham maior ocorrência de referir IU, mas apenas a associação com a condição dona de casa foi significante. Quanto ao diabetes, idosas que tinham a doença (RP 1,57 IC95% 1,16-2,13) tinham maior frequência de referir queixa de IU quando comparadas às idosas sem diabetes. Conclusão: Encontrou-se uma elevada prevalência de Incontinência Urinária em idosas, correspondendo a quase metade das mulheres investigadas, estando associada às idosas de maior idade, donas de casa e diabéticas.
The scales are linked with the classification at different levels. The International Consultation on Incontinence Questionnaire was the most limited instrument. Bristol Female Urinary Tract Symptoms Questionnaire and Incontinence Quality of Life Questionnaire presented greater agreement with the ICF, but the concepts in their items are mostly linked to body functions, denoting a biomedical vision. King's Health Questionnaire demonstrated greater affinity with the ICF, and most concepts were related to the activities and participation categories, approaching more effectively the biopsychosocial model. Implications for Rehabilitation Choosing the right instrument to assess the quality of life of women with urinary incontinence can be a difficult task, since the instruments have different approaches. The use of International Classification of Functioning, Disability and Health as a reference among health professionals involved in rehabilitation of women with urinary incontinence will promote unification of the language about this group functioning. The comparison among instruments presented here will help the professional to choose the one that provides the greatest amount of information in a consistent way, aiding the clinical decision-making process.
Objective: To analyse the influence of exclusive breastfeeding and associated factors on the neurodevelopment (ND) of children up to 36 months old. Methods: A cross-sectional, community-based study with individuated data of 99 children up to 36 months old, evaluated socio demographic, obstetric and neonatal variables and assessed ND through the Development Monitoring Instrument. The variables were analysed using descriptive statistics and regression testing. Data were considered significant when p <0.05.Results: : Regarding ND, 70.71% of the children had achieved the motor milestones for their age, 98.99% of mothers breastfed, 37.38% of them had exclusive breastfed (EBF) for six months. Factors that positively influenced the ND were vaginal delivery when compared to children with other types of delivery, and EBF for 6 months when compared to children who had EBF less than six months. Conclusion: The practice of exclusive breastfeeding for less than six months is associated with a higher prevalence of lower psychomotor development of children from zero to 36 months old. Other factors associated with delay in development are instrumented vaginal delivery with forceps or caesarean delivery. Open acess Keywords 159J Hum Growth Dev. 2017; 27(2): 158-165 Association between breastfeeding, obstetric factors and child development in northeast Brazil
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