Os bancos de leite humano (HMBs) estão sujeitos a doações reduzidas e coleta de descarte para processamento. Objetivo: Identificar as causas do desperdício de leite humano no HMB. Materiais e métodos: Estudo descritivo, retrospectivo e transversal dos dados secundários registrados nos arquivos dos prontuários no HMB Information durante o processamento, sendo necessário identificar as principais causas de desperdício do Sistema de um hospital público terciário, em relação a doadores de leite humano e recém-nascidos receptores, entre janeiro e dezembro de 2000. 2017. A análise estatística descritiva foi realizada pelo Statistic Package for the Social Sciences versão 25.0. Resultados: foram selecionados 383 doadores e 149 recém-nascidos que receberam leite humano que possuíam registros completos no sistema. Do volume inicial (711.854,14 mL de leite humano), o 13. 74% dos resíduos foram concentrados nas fases de seleção e classificação (9,04%). As causas do desperdício de leite humano foram acidez Dornic (6,98%), condição de sabor desagradável (5,50%) e sujeira (2,01%). O desperdício de leite humano concentrado na fase de seleção e classificação. Conclusão: As causas do desperdício de amostra nas fases de seleção e classificação são a alta acidez Dornic, a condição de sabor ruim e a sujeira. A recomendação é orientar a coleta pela equipe do HMB aos doadores para reduzir o desperdício no banco de leite humano. condição sem sabor e sujeira. A recomendação é orientar a coleta pela equipe do HMB aos doadores para reduzir o desperdício no banco de leite humano. condição sem sabor e sujeira. A recomendação é orientar a coleta pela equipe do HMB aos doadores para reduzir o desperdício no banco de leite humano.
To evaluate the effects of oxidative stress in pregnant rats submitted to acute and chronic stress, relating to alterations in the uterus, placenta and fetus. Methods: Twenty-four female Wistar albino (Rattus norvegicus), were divided into four groups, for induction of oxidative stress the animals were submitted to cold and physical immobilization. Plasma fasting glucose and MDA were determined in all groups and the fetuses and placentas were measured. Results: There were no statistical differences in the levels of malonic dialdehyde (MDA), however the averages of chronic stress group were higher compared to control groups, which could explain the observed adverse effects; there was no correlation between puppies' size, the weight of the placenta and MDA values. Conclusions: Chronic stress causes adverse effects, when compared to control groups; chronic stress group had fetuses, placentas and number of puppies, significantly lower compared to other groups. The rats exposed to chronic stress, also presented a higher frequency of fetal resorption.
This work aimed to approach Sickle Cell Anemia from the standpoint of medical anthropology, from the perspective of health, disease and culture, not only addressing the disease as a biological event, but also other socio-cultural aspects of the individual. This is a descriptive, theoretical-reflexive analysis-type study. Seeking to know the disease, its treatment and complications within the socio-cultural context are important to contribute to possible changes in the perspective with the individual regarding this morbidity. Having the field of public health in development, an approach beyond the technical molds for the treatment of diseases, a multidisciplinary approach is needed to meet the needs of the population, to provide patient-centered care for their social, psychological and cultural context.
Objetivo: descrever os aspectos espaciais e padrões temporais da rápida propagação da Doença falciforme no Estado do Mato Grosso do Sul (Brasil) e identificar possíveis fatores de risco no estado. Método: Estudo quantitativo, descritivo e analítico, com uso do delineamento de pesquisa de análise geoespacial do estado de Mato Grosso do Sul, no período de 2001 a 2014. A distribuição do HbAS e HbSS foi mapeada, com uso do software ArcGIS 10.3.1. Resultados: A doença apresentou-se de forma endêmica no estado de Mato Grosso do Sul de 2001 a 2014. Análises geoespaciais e temporais indicaram que a expansão e distribuição ocorreu de forma progressiva. Conclusão: Os resultados permitem relacionar a expansão da doença ao intenso tráfico humano ao longo das rotas de cultivo de soja. Outros estudos que investiguem os haplótipos da população devem ser realizados no intuito de suprir falhas referentes aos fluxos migratórios naquela região.
Objective: To estimate the occurrence of acute events in hospitalized patients with sickle cell anemia (SCA) before and after the use of hydroxyurea (HU). Method: The study has a quantitative approach, of analytical cohort type developed in two public referral hospitals in the Midwest region of Brazil, from November 2010 to October 2011. Data collection was performed on records of patients diagnosed with SCA. The interval time for the data collection was 30 years, which corresponded between 1980 and 2010. The research was approved by the Ethics Committee of the Federal University of Mato Grosso do Sul, Campo Grande/MS, Brazil, under protocol 1822/2010. Results: The sample had 32 medical records of hospitalized patients diagnosed with SCA who used HU. The mean age of the participants was 25.65±11.92; the average time of drug exposure was 6.0±2.8 years; the average initial dose was 17.00±5.3mg/kg/day and final dose of 22.10±5.3 mg/kg/day. After using HU, the fetal hemoglobin ranged from 8.41±0.95 to 14.44±13.7% (p<0.001). There was a reduction of the average leucocyte, absolute neutrophil, acute events, total infections and blood transfusions. Conclusion: The effects of HU exposure caused an increase in fetal hemoglobin level, decreasing leukocyte, absolute neutrophils and acute events, transfusions and hospitalizations by the use of non-opioid.
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