Recently, underwater wireless sensor networks (UWSNs) have attracted much research attention from both academia and industry, in order to explore the vast underwater environment. UWSNs have peculiar characteristics; that is, they have large propagation delay, high error rate, low bandwidth, and limited energy. Therefore, designing network/routing protocols for UWSNs is very challenging. Also, in UWSNs, improving the energy efficiency is one of the most important issues since the replacement of the batteries of underwater sensor nodes is very expensive due to the unpleasant underwater environment. In this paper, we therefore propose an energy efficient routing protocol, named (energy-efficient depth-based routing protocol) EEDBR for UWSNs. EEDBR utilizes the depth of sensor nodes for forwarding data packets. Furthermore, the residual energy of sensor nodes is also taken into account in order to improve the network lifetime. Based on the comprehensive simulation using NS2, we observe that EEDBR contributes to the performance improvements in terms of the network lifetime, energy consumption, and end-to-end delay. A previous version of this paper was accepted in AST-2011 conference.
Background Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Methods We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0•9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0•9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124.
Abstract. Recently, Underwater Wireless Sensor Networks (UWSNs) have attracted much research attention from both academia and industry, in order to explore the vast underwater environment. However, designing network protocols is challenging in UWSNs since UWSNs have peculiar characteristics of large propagation delay, high error rate, low bandwidth and limited energy. In UWSNs, improving the energy efficiency is one of the most important issues since the replacement of the batteries of such nodes is very expensive due to harsh underwater environment. Hence, in this paper, we propose an energy efficient routing protocol, named EEDBR (Energy-Efficient Depth Based Routing protocol) for UWSNs. Our proposed protocol utilizes the depth of the sensor nodes for forwarding the data packets. Furthermore, the residual energy of the sensor nodes is also taken into account in order to improve the network life-time. Based on the comprehensive simulation using NS2, we observe that our proposed routing protocol contributes to the performance improvements in terms of the network lifetime, energy consumption and end-to-end delay.
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