Aim: Reporting the case of a patient with Edwards syndrome of above-average survival. Edwards syndrome is a chromosomal disorder with multiple and severe congenital malformations, a profound delay in neuropsychomotor development, and an average survival of around 2.5 to 14.5 days. Description: Patient age of seven years and six months, female, who presented at birth, congenital heart disease, microcephaly, micrognathia, cutis marmorata, pectus escavatum and other typical alterations of Edwards Syndrome. Intensive interventions were performed, and karyotype exam confirmed full trisomy of chromosome 18. The patient currently undergoes intensive occupational and speech-language therapy, physiotherapy, and is stable. Comments: Edwards syndrome has a reserved prognosis, and although it is proven that aggressive interventions improve the survival of these patients, there is still no consensus in neonatal resuscitation protocols, and there are differences in perception about prognosis and therapeutic recommendations. However, parental autonomy must always be considered, and it is known that patients who survive to childhood bring positive results in the family circle. The discussion of prognosis and therapy is necessary and should aim at the homogenization of medical conduct.
Breast cancer is a multifactorial disease that have been increasing in an alarm rate worldwide, and has overweight and obesity as important risk factors, being considered a significant public health problem. The present study aimed to demonstrate the clinical and epidemiological profile of breast cancer patients diagnosed in Sinop-MT (Brazil) and analyze the prevalence of overweight and obesity in these patients. This is a descriptive study, with data collected by analysis of patient’s medical records who were diagnosed with breast carcinoma in the Department of Oncology of Santo Antônio’s Hospital. Data were tabulated and analyzed in an Excel® spreadsheet software (Office 365), with a descriptive analysis in percentage. Results demonstrated that 100% of patients were women; 85.7% were affected by ductal and/or lobular breast carcinomas; all deaths occurred in patients over 40 years and 75% of deaths occurred in advanced stages; being 68.75% of the most severe cases’ stages present in the oldest patients. Furthermore, it was observed that 37.12% of the patients were classified as overweight or obese, 88.57% were treated with chemotherapy and 91.44% treated with combined therapies. In conclusion, it was observed that a great number of breast cancer patients were overweight/obese, presented ductal and lobular carcinoma, the deaths occurred predominantly in the over forty years and were related with the presence of metastasis and advanced stage.
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