Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

Abstract

There are 230 to 240 known Bidens species. Among them, Bidens pilosa is a representative perennial herb, globally distributed across temperate and tropical regions. B. pilosa has been traditionally used in foods and medicines without obvious adverse effects. Despite significant progress in phytochemical and biological analyses of B. pilosa over the past few years, comprehensive and critical reviews of this plant are anachronistic or relatively limited in scope. The present review aims to summarize up-to-date information on the phytochemistry, pharmacology, and toxicology of B. pilosa from the literature. In addition to botanical studies and records of the traditional use of B. pilosa in over 40 diseases, scientific studies investigating the potential medicinal uses of this species and its constituent phytochemicals for a variety of disorders are presented and discussed. The structure, bioactivity, and likely mechanisms of action of B. pilosa and its phytochemicals are emphasized. Although some progress has been made, further rigorous efforts are required to investigate the individual compounds isolated from B. pilosa to understand and validate its traditional uses and develop clinical applications. The present review provides preliminary information and gives guidance for further basic and clinical research into this plant.

Antioxidant activities of Moringa oleifera L. and Bidens pilosa L. leaf extracts and their effects on oxidative stability of ground raw beef during refrigeration storage

“…plant families are known to contain rich antioxidant compounds (Adedapo, Jimoh, & Afolayan, 2011;Moyo, Masika, Hugo, & Muchenje, 2012). The leave of these plants have been used for centuries as dietary ingredients or supplements (Bartolome, Villaseñor, & Yang, 2013;Hazra, Biswas, Bhattacharyya, Das, & Khan, 2012). Recent studies on their application have showed that they possess great biological activities such as anti-diabetes, antitumor, anti-inflammation, anticancer and antibacterial (Bartolome et al, 2013;Dai & Mumper, 2010).…”

“…The leave of these plants have been used for centuries as dietary ingredients or supplements (Bartolome, Villaseñor, & Yang, 2013;Hazra, Biswas, Bhattacharyya, Das, & Khan, 2012). Recent studies on their application have showed that they possess great biological activities such as anti-diabetes, antitumor, anti-inflammation, anticancer and antibacterial (Bartolome et al, 2013;Dai & Mumper, 2010). Reports on their nutritional contents have also showed that they are rich in proteins (including essential amino acids), vitamins, beta-carotene, minerals and low in fat and carbohydrates (Adedapo et al, 2011;Moyo et al, 2012;Bartolome et al, 2013).…”

“…Recent studies on their application have showed that they possess great biological activities such as anti-diabetes, antitumor, anti-inflammation, anticancer and antibacterial (Bartolome et al, 2013;Dai & Mumper, 2010). Reports on their nutritional contents have also showed that they are rich in proteins (including essential amino acids), vitamins, beta-carotene, minerals and low in fat and carbohydrates (Adedapo et al, 2011;Moyo et al, 2012;Bartolome et al, 2013). The antioxidant and biological activities of these plants have been attributed to the presence of phytochemicals including flavonoids and other phenolics in their leaves extract (Al-Owaisi, Al-Hadiwi, & Khan, 2014;Falowo, Muchenje, Hugo, & Charimba, 2016).…”

In vitro antimicrobial activities of Bidens pilosa and Moringa oleifera leaf extracts and their effects on ground beef quality during cold storage

“…Both plants are considered as potential functional ingredients and promising sources of natural antioxidants (Bartolome, Villaseñor, & Yang, 2013;Sreelatha & Padma, 2009). Conventionally, almost all parts of these plants (the whole plant, the aerial parts and/or the roots) have been used on an extensive basis, either as food or medicinal components (Yang, 2014).…”

“…The leaves are particularly rich in protein, essential amino acids and other micronutrients (Adedapo, Jimoh, & Afolayan, 2011;Moyo, Masika, Hugo, & Muchenje, 2011;Yassa & Tohamy, 2014). The extracts of both plants have been identified to possess several functional properties, such as antioxidant, antihypertensive, antimicrobial, antifungal, antiulcer, antitumor and anticancer activities (Bartolome et al, 2013). The in vitro activity of plant extracts have also been reported against several foodborne and human pathogenic microorganisms including Klebsiella, Bacillus, Pseudomonas, Staphylococcus, Salmonella and Escherichia coli (Khan, Kihara, & Omoloso, 2001;Rahman et al, 2010).…”